Some considerations about acquired adult and pediatric cholesteatomas.

Some considerations about acquired adult and pediatric cholesteatomas Summary

Galectin-1, -3, -7 Expressions in Congenital and Acquired Pediatric Cholesteatomas Compared to External Auditory Canal Skin

OBJECTIVES There is a classical distinction based on clinical criteria between acquired and congenital cholesteatomas. To determine if these two types of lesions show different immunohistochemical features, we have studied the expression patterns of three distinctive galectins (animal lectins implied especially in cellular proliferation and apoptosis) in both types of cholesteatomas and compare...

Surgical treatment of pediatric cholesteatomas.

OBJECTIVE : Management of pediatric cholesteatomas remains controversial. We reviewed our 16-year experience in the surgical treatment of cholesteatomas in children and describe a treatment paradigm. STUDY DESIGN : The authors conducted a retrospective review. METHODS : A total of 106 mastoidectomies (86 for an acquired cholesteatoma and 20 for a congenital cholesteatoma) were performed in ...

Differential Protein Expression in Congenital and Acquired Cholesteatomas

Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intact eardrum. Congenital and acquired cholesteatomas progress quite differently from each other and progress patterns can provide clues about the unique origin and pathogenesis of the abnormality. However, the exact pathogenic mechanisms by which cholesteatomas develop remain unknown. In this study,...

Morphological considerations about middle ear cholesteatoma.

The aim of this study is to present various morphologic aspects of the middle ear cholesteatoma, concerning both container (tympanic cavity) and content (cholesteatoma). There are two different aspects of the study: a mezoscopic study of the tympanic walls and the elements within the middle ear (ossicular chain, folds, ligaments, middle ear clefts) in order to evidentiate the critical areas (si...